Undergraduate Catalog 2014-2015
BIO 425 Computational Molecular Biology
3 hours; 3 credits
Overview of theoretical and computational methods in bioinformatics with an emphasis on the application of algorithms and use of statistical methods in nucleic acid and protein sequence analysis. Emphasis on the mathematical basis of sequence alignment including database searches using Smith-Waterman dynamic programming, pair-wise sequence alignment using dynamic programming and scoring matrices, and multiple sequence alignment using hidden Markov model and genetic algorithms.
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