: Building 6S
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Ph. D., Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
M.S., Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
B.S., Lanzhou University, P. R. China
Biography / Academic Interests
Dr. Hu’s research is multi-disciplinary including transition metal catalysis, organocatalysis, novel macromolecule synthesis and bioactive compound synthesis is undergoing in my laboratory. Transition metal-catalyzed and organic compound-catalyzed C-C and C-X (X = O, N, etc) bond formations are among the most powerful transformations in organic synthesis and related fields. Development of highly efficient ligands/catalysts represents one of the most important goals in organic/organometallic chemistry. The central theme of Dr. Hu’s research is to develop new ligands/catalysts and new reactions for organic synthesis. He is currently investigating the following related aspects of transition metal catalysis/organocatalysis: (a) design and synthesis of new ligands including phosphines and phosphites for transition metal catalysis, (b) design and synthesis of novel transition metal catalysts for new catalytic reactions, (c) design and synthesis of new organocatalysts, e. g., chiral diol-based Bronsted acids, for asymmetric catalysis, (d) development of new reactions/processes, (e) development of novel macromolecules including polymers and dendrimers for catalytic reactions including asymmetric catalysis, (f) design and synthesis of novel materials with tailored properties, and (g) application of the newly developed catalysts/reactions to the synthesis of biologically active compounds.
Scholarship / Publications
A nontransmetalation reaction pathway for anionic four-electron donor-based palladacycle-catalyzed addition reactions of arylborons with aldehydes. Liao, Y.-X.; Xing, C.-H.; Israel, M.; Hu, Q.-S. Tetrahedron Lett. 2011, 52, 3324-3328.
Fluorenone Synthesis by Palladacycle-Catalyzed Sequential Reactions of 2-Bromobenzaldehydes with Arylboronic Acids. Liu, T.-P.; Liao, Y.-X.; Xing, C.-H.; Hu, Q.-S. Org. Lett. 2011, 13, 2452-2455.
Optically Active 1,1-Spirobiindane-7,7-diol (SPINOL)-Based Phosphoric Acids as Highly Enantioselective Catalysts for Asymmetric Organocatalysis. Xing, C.-H.; Liao, Y.-X.; Ng, J.; Hu, Q.-S. J. Org. Chem. 2011, 76, 4125-4131.
Sequential Aldol Condensation-Transition Metal-Catalyzed Addition Reactions of Aldehydes, Methyl Ketones and Arylboronic Acids. Liao, Y.-X.; Xing, C.-H.; Israel, M.; Hu, Q.-S. Org. Lett. 2011, 13, 2058-2061.
Tandem Reaction Synthesis of Fluorenes/Indenofluorenes Based on Pd(OAc)2/PCy3-Catalyzed Suzuki Cross-Coupling and C-H Bond Activation Strategy. Liu, T.-P.; Hu, Q.-S. Angew. Chem. Int. Ed. 2010, 49, 2909-2912.
Preferential Oxidative Addition in Palladium(0)-Catalyzed Suzuki Cross-Coupling Reactions of Dihaloarenes with Arylboronic Acids. Dong, C.-G.; Hu, Q.-S. J. Am. Chem. Soc. 2005, 127, 10006-10007.