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PhD, State University of New York at Stony Brook
BA, State University of New York, College at Oswego
Biography / Academic Interests
Dr. McCloskey’s research is focused on understanding the ways that neurons participate in networks to produce complex behaviors such as learning, memory, and mood. The brain uses patterns of rhythm and synchrony to accomplish these tasks, but the amount of synchrony required is a delicate balance. Too little, and the brain will not develop properly. Too much, and seizures can occur. The McCloskey Laboratory at the College of Staten Island uses a combination of anatomy, physiology, and behavior to study the mammalian brain to understand how networks achieve this balance, and what interventions can help to restore it.
Scholarship / Publications
Pierce, J. P., Punsoni, M., McCloskey, D. P., & Scharfman, H. E. (2011). The morphometry of hilar ectopic granule cells in the rat. Journal of Comparative Neurology, In Press.
Anderson, B. J., Greenwood, S. J., & McCloskey, D. P. (2010). Exercise as an intervention for the age-related decline in brain metabolic support. Frontiers in Aging Neuroscience, 2, 30.
Scharfman, H. E., & McCloskey, D. P. (2009) Postnatal neurogenesis as a therapeutic target in temporal lobe epilepsy. Epilepsy Research, 85(2), 150-161
Scharfman, H.E. Malthankar-Phatak, G.H., Friedman D,, Pearce BP, McCloskey D.P. Harden C.J.,and MacLusky N.L. (2009). A Rat Model of Epilepsy in Women: a Tool to Study Physiological Interactions Between Endocrine Systems and Seizures. Endocrinology, 150(9), 4437-4442.
McCloskey, D. P., Hintz, T. M., & Scharfman, H. E. (2008). Plasticity and electrophysiological effects of vascular endothelial growth factor on motor neurons. Brain Research Bulletin 76(1-2), 36-44.
Nicoletti, J. N., Shah, S. K., Goodman, J. H., McCloskey, D. P., Elkady, A., Solla, A., Hylton, D., Rudge, J. S., Scharfman, H. E., & Croll, S. D. (2008). Vascular endothelial growth factor (VEGF) is upregulated after status epilepticus and protects against seizure-induced neuronal loss. Neuroscience, 151(1), 232-241