After she got her Ph.D. in 1996, Dr. Zhou worked as a Postdoc Research Associate at SUNY at Stony Brook. During 2000-2002, she worked as a Senior Chemist in Union Carbide/The Dow Chemical Company to develop personal care products. She joined to CSI as an Associate Professor in 2002 and was promoted to Professor in 2008.
Prof. Zhou’s current research interests include:
• Design, synthesis, and characterization of novel glucose-sensitive nanoparticles and microgels for glucose sensing and self-regulated insulin delivery
• Multifunctional nanomaterials from the combination of inorganic nanoparticles with responsive polymers for sensing, imaging, and drug delivery in biomedical applications
• Composite nanomaterials from the supramolecular assembly of fullerene derivatives, surfactants, and organic dyes in the specific confinement of polymers and colloids
• Self-assembly/association of nanoparticles, lipids, collagens, and other functional amphiphiles
• Nanostructure and morphology study of materials using Light scattering and X-ray scattering
Ph.D. The Chinese University of Hong Kong
M. S. Xiamen University, China
B. S. Xiamen University, China
Scholarship / Publications
H. Wang, Q. Chen, S. Zhou. Carbon-based hybrid nanogels: a synergistic nanoplatform for combined biosensing, bioimaging, and responsive drug delivery, Chem. Soc. Rev. 2018, 47, 4198-4232.
H. Wang, S. Mukherjee, J. Yi, P. Banerjee, Q. Chen, S. Zhou Biocompatible Chitosan–Carbon Dot Hybrid Nanogels for NIR-Imaging-Guided Synergistic Photothermal–Chemo Therapy, ACS Appl. Mater. Interfaces 2017, 9, 18639-18649.
H. Wang, Q. Mu, R. Revia, K. Wang, X. Zhou, P. J. Pauzauskie, S. Zhou, M. Zhang Chitosan-Gated Magnetic-Responsive Nanocarrier for Dual-Modal Optical Imaging, Switchable Drug Release, and Synergistic Therapy, Adv. Healthcare Mater. 2017, 6, 1601080.
H. Wang, K. Wang, Q. Mu, Zachary R. Stephen, Yanyan Yu, S. Zhou, M. Zhang. Mesoporous carbon nanoshells for high hydrophobic drug loading, multimodal optical imaging, controlled drug release, and synergistic therapy. Nanoscale, 2017, 9, 1434-1442.
H. Wang, J. Yi, Y. Yu, S. Zhou NIR upconversion fluorescence glucose sensing and glucose-responsive insulin release of carbon dot-immobilized hybrid microgels at physiologcial pH, Nanoscale. 2017, 9, 509-516.
A. Chang, Y. Peng, Z. Li, X. Yu, K. Hong, S. Zhou, W. Wu. Assembly of polythiophenes on responsive polymer microgels for the highly selective detection of ammonia gas. Polym. Chem., 2016, 7, 3179-3188.
H. Wang, S. Zhou. Magnetic and fluorescent carbon-based nanohybrids for multi-modal imaging and magnetic field/NIR light responsive drug carriers. Biomater. Sci., 2016, 4, 1062-1073.
H. Wang, J. Zhuang, D. Velado, Z. Wei, H. Matsui, S. Zhou. Near-infrared- and visible-light-enhanced metal-free catalytic degradation of organic pollutants over carbon-dot-based carbocatalysts synthesized from biomass. ACS Appl. Mater. Interfaces 2015, 7, 27703-27712.
H. Wang, J. Di, Y. Sun, J. Fu, Z. Wei, H. Matsui, A. del C. Alonso, S. Zhou. Biocompatible PEG-chitosan@carbon dots hybrid nanogels for two-photon fluorescence imaging, near-infrared light/pH dual-responsive drug carrier and synergistic therapy. Adv. Func. Mater., 2015, 25, 5537-5547.
H. Wang, J. Yi, D. Velado, Y.Yu, S. Zhou. Immobilization of Carbon Dots in Molecularly Imprinted Microgels for Optical Sensing of Glucose at Physiological pH. ACS Appl. Mater. Interfaces 2015, 7, 15735-15745.
H. Wang, G. Cao, Z. Gai, K. Hong, P. Banerjee, S. Zhou. Magnetic/NIR-responsive drug carrier, multicolor cell imaging, and enhanced photothermal therapy of gold capped magnetite-fluorescent carbon hybrid nanoparticles. Nanoscale. 2015, 7, 7885-7895.
H. Wang, Y. Sun, J. Yi, J. Fu, J. Di, A. del C. Alonso, S. Zhou. Fluorescent porous carbon nanocapsules for two-photon imaging, NIR/pH dual-responsive drug carrier, and photothermal therapy. Biomaterials, 2015, 53, 117-126.
H.Wang, J. Yi, S. Mukherjee, P. Banerjee, S. Zhou. Magnetic/NIR-thermally responsive hybrid nanogels for optical temperature sensing, tumor cell imaging and triggered drug release. Nanoscale, 2014, 6, 13001–13011.
H. Wang, A. Mararenko, G. Cao, Z. Gai, K. Hong, P. Banerjee, S. Zhou. Multifunctional 1D magnetic and fluorescent nanoparticle chains for enhanced MRI, fluorescent cell imaging, and combined photothermal/chemotherapy. ACS Appl. Mater. Interfaces 2014, 6, 15309–15317.
H. Wang, Z. Wei, H. Matsui, S. Zhou. One-pot synthesis of Fe3O4@Carbon quantum dots hybrid nanoflowers for highly active and recyclable visible-light driven photocatalyst. J. Mater. Chem. A, 2014, 2, 15740-15745.
H. Wang, F. Ke, A. Mararenko, Z. Wei, P. Banerjee, S. Zhou. Responsive polymer-fluorescent carbon nanoparticle hybrid nanogels for optical temperature sensing, near-infrared light-responsive drug release, and tumor cell imaging, Nanoscale, 2014, 6, 7443-7452.
H. Wang, J. Shen, Y. Li, Z. Wei, G. Cao, Z. Gai, K. Hong, P. Banerjee, S. Zhou. Magnetic Iron Oxide-Fluorescent Carbon Dots Integrated Nanoparticles for Dual-modal Imaging, Near-infrared Light-responsive Drug Carrier and Photothermal Therapy. Biomaterials Sci., 2014, 2, 915-923.
H. Wang, J. Shen, G. Cao, Z. Gai, K. Hong, P. R. Debata, P. Banerjee, S. Zhou. Multi-functional PEG encapsulated Fe3O4@silver hybrid nanoparticles: antibacterial activity, cell imaging and combined photothermo/chemo-therapy. J. Mater. Chem. B., 2013, 1, 6225-6234.
H. Wang, J. Shen, Y. Li, Z. Wei, G. Cao, Z. Gai, K. Hong, P. Banerjee, S. Zhou. Porous Carbon Protected Magnetite and Silver Hybrid Nanoparticles: Morphological Control, Recyclable Catalysts, and Multicolor Cell Imaging. ACS Appl. Mater. Interfaces 2013, 5, 9446−9453
Y. Li, S. Zhou. Facile one-pot synthesis of organic dye-complexed microgels for optical detection of glucose at physiological pH. Chem. Commun. 2013, 49, 5553-5555.
W. Wu, S. Zhou. Responsive materials for self-regulated insulin delivery. Macromol. Biosci. 2013, 11, 1464-1477. (Invited Feature Article)
Y. Li, S. Zhou. A simple method to fabricate fluorescent glucose sensor based on dye-complexed microgels. Sens. Actuators B Chem. 2013, 177, 792-799.
T. Zhou, C. Xiao, J. Fan, S. Chen, J. Shen, W. Wu, S. Zhou. A nanogel of on-site tunable pH-response for efficient anticancer drug delivery. Acta Biomaterialia 2013, 9, 4546-4557.
W. Wu, S. Zhou. Responsive polymer-inorganic hybrid nanogels for optical sensing, imaging, and drug delivery. In "Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering", Ashutosh Tiwari and Atul Tiwari, Eds.; Wiley-Scrivener Publishing, USA, 2013, Chapter 8, pp. 269-320.
C. Xiao, S. Chen, L. Zhang, S. Zhou, W. Wu. One-pot synthesis of responsive catalytic Au@PVP hybrid nanogels. Chem. Commun. 2012, 48, 11751-11753.
J. Shen, T. Ye, A. Chang, W. Wu, S. Zhou. A colloidal supra-structure of responsive microgels as potential cell scaffold. Soft Matter 2012, 8, 12034-12042.
W. Wu, S. Chen, Y. Hu, S. Zhou. A fluorescent responsive hybrid nanogel for closed loop control of glucose. J. Diabetes Sci. Technol. 2012; 6, 892-901.
W. Wu, J. Shen, Y. Li, H. Zhu, P. Banerjee, S. Zhou. Specific glucose-to-SPR signal transduction at physiological pH by molecularly imprinted responsive hybrid microgels. Biomaterials 2012, 33, 7115-7125.
H. Zhu, Y. Li, R. Qiu, L. Shi, W. Wu, S. Zhou. Responsive fluorescent Bi2O3@PVA hybrid nanogels for temperature-sensing, dual-modal imaging, and drug delivery. Biomaterials 2012, 33, 3058-3069.
W. Wu, J. Shen, Z. Gai, K. Hong, P. Banerjee, S. Zhou. Multifunctional core-shell hybrid nanogels for pH-dependent magnetic manipulation, fluorescent pH-sensing, and drug delivery. Biomaterials 2011, 32, 9876-9887.
W. Wu, J. Shen, P. Banerjee, S. Zhou. A multifuntional nanoplatform based on responsive fluorescent plasmonic ZnO-Au@PEG hybrid Nanogels. Adv. Func. Mater., 2011, 21, 2830-2839.
Z. H. Farooqi, W. Wu, S. Zhou, Mohammad Siddiq. Engineering of Phenylboronic Acid Based Glucose-Sensitive Microgels with 4-Vinylpyridine for Working at Physiological pH and Temperature. Macromol. Chem. Phys. 2011, 212, 1510-1514.
W. Wu, J. Shen, P. Banerjee, S. Zhou. Water-dispersible multifunctional hybrid nanogels for combined curcumin and photothermal therapy. Biomaterials, 2011, 32, 598-609.
W. Wu, S. Zhou. Hybrid micro-/nanogels for optical sensing and intracellular imaging. Nano Reviews, 2010, 1, 5730.
W. Wu, J. Shen, P. Banerjee, S. Zhou. Chitosan-based responsive Hybrid nanogels for integration of optical pH-sensing, tumor cell imaging and controlled drug delivery. Biomaterials, 2010, 31, 8371-8381.
W. Wu, J. Shen, P. Banerjee, S. Zhou. Core-shell hybrid nanogels for Integration of optical temperature-sensing, targeted tumor cell imaging, and combined chemo-photothermal treatment. Biomaterials, 2010, 31, 7555-7566.
T. Zhou, W. Wu, S. Zhou. Engineering Oligo(ethylene glycol)-Based Thermosensitive Microgels for Drug Delivery Applications. Polymer, 2010, 51, 3926-3933.
W. Wu, N. Mitra, E.C. Y. Yan, S. Zhou. Multifunctional Hybrid Nanogel for Integration of Optical Glucose Sensing and Self-Regulated Insulin Release at Physiological pH. ACS Nano, 2010, 4, 4831–4839.
W. Wu, T. Zhou, A. Berliner, P. Banerjee, S. Zhou. Glucose Mediated Assembly of Phenylboronic Acid Modified CdTe/ZnTe/ZnS Quantum Dots for Intracellular Glucose Probing. Angew. Chem. Int. Ed., 2010, 49, 6554-6558.
W. Wu, T. Zhou, M. Aiello, S. Zhou. Construction of optical glucose nanobiosensor with high sensitivity and selectivity at physiological pH on the basis of organic-inorganic hybrid microgels. Biosens. Bioelectron. 2010, 25, 2603-2610.
H. Yan, S. Lim, Y. Zhang, Q. Chen, D. Mott, W. Wu, D. An, S. Zhou, C.J. Zhong. Rigid, Conjugated and Shaped Aryl Ethynyl Mediators for Assembly of Nanoparticles. Chem. Commun. 2010, 46, 2218-2220.
W. Wu, T. Zhou, A. Berliner, P. Banerjee, S. Zhou. Smart Core-Shell Hybrid Nanogels with Ag Nanoparticle Core for Cancer Cell Imaging and Gel Shell for pH-Regulated Drug Delivery. Chem. Mater., 2010, 22, 1966-1976.
W. Wu, M. Aiello, T. Zhou, A. Berliner, P. Banerjee, S. Zhou. In-situ immobilization of quantum dots in polysaccharide-based nanogels for integration of optical pH-sensing, tumor cell imaging, and drug delivery. Biomaterials, 2010, 31, 3023-3031.